Here is tool to create USB live with Windows 10 .ISO
Windows USB/DVD Download Tool
http://wudt.codeplex.com/
Alternative tool
ISO to USB
http://www.isotousb.com/
Othewise if you need to create a full backup of an USB drive
http://www.osforensics.com/tools/write-usb-images.html
[more explanation https://www.microsoft.com/en-us/download/windows-usb-dvd-download-tool]