If you have necessity to protect some folders using passwords/encryption using as single repository (where copy/modify/delete folders/Files) consider that 7zip has a simple feature that permit to get this result.
An alternative way is using EFS (more secure) or attaching .VHD file and proceeding, furthermore, to apply bitlocker encryption.
Here they are related articles useful to go deeper on this topic.
7zip, EFS
https://helpdeskgeek.com/windows-10/how-to-password-protect-a-folder-in-windows-10/
Bitlocker e VHD